Table of Contents

Section 1: Whole Larvae: G85R vs. WT DEGs

  • Figure 1: G85R vs WT Controls

  • Figure 2: G85R vs WT TKT-Df

  • Figure 3: G85R vs WT TKT-OE



Section 2: Whole Larvae: Control vs TKT-Df DEGs

  • Figure 4: Control vs TKT-Df Females

  • Figure 5: Control vs TKT-Df Males



Section 3: Whole Larvae: Control vs TKT-OE DEGs

  • Figure 6: Control vs TKT-OE Females

  • Figure 7: Control vs TKT-OE Males



Section 4: Larval Brains: LL3 vs ML3 DEGs

  • Figure 8: LL3 vs ML3

  • Figure 9: LL3 vs ML3 (alternative plot style)




Section 1: Whole Larvae: G85R vs. WT DEGs

Figure 1: G85R vs WT Control data. Plotting all genes that are significantly differentially expressed in both males and females. Red are synaptic genes with increased expression in G85R, blue decreased. Grey are known Tfs and purple are ChIP validated TFs.




Figure 2: G85R vs WT TKT-Df data. Plotting all genes that are significantly differentially expressed in both males and females. Red are synaptic genes with increased expression in G85R, blue decreased. Grey are known Tfs and purple are ChIP validated TFs.




Figure 3: G85R vs WT TKT-OE data. Plotting all genes that are significantly differentially expressed in both males and females. Red are synaptic genes with increased expression in G85R, blue decreased. Grey are known Tfs and purple are ChIP validated TFs.




Section 2: Whole Larvae: Control vs TKT-Df DEGs

Figure 4: Control vs TKT-Df data for Female G85R and WT samples. Plotting all genes that are exclusively significantly differentially expressed in G85R or WT comparisons but not those that are shared. Red are synaptic genes with increased expression in G85R, blue decreased. Grey are known Tfs and purple are ChIP validated TFs.




Figure 5: Control vs TKT-Df data for Male G85R and WT samples. Plotting all genes that are exclusively significantly differentially expressed in G85R or WT comparisons but not those that are shared. Red are synaptic genes with increased expression in G85R, blue decreased. Grey are known Tfs and purple are ChIP validated TFs.




Section 3: Whole Larvae: Control vs TKT-OE DEGs

Figure 6: Control vs TKT-OE data for Female G85R and WT samples. Plotting all genes that are exclusively significantly differentially expressed in G85R or WT comparisons but not those that are shared. Red are synaptic genes with increased expression in G85R, blue decreased. Grey are known Tfs and purple are ChIP validated TFs.




Figure 7: Control vs TKT-Df data for Male G85R and WT samples. Plotting all genes that are exclusively significantly differentially expressed in G85R or WT comparisons but not those that are shared. Red are synaptic genes with increased expression in G85R, blue decreased. Grey are known Tfs and purple are ChIP validated TFs.




Section 4: Larval Brains: LL3 vs ML3 DEGs

Figure 8: Late-L3 vs Mid-L3 G85R and WT samples. Plotting all genes that are exclusively significantly differentially expressed in G85R or WT comparisons but not those that are shared. Red are synaptic genes with increased expression in G85R, blue decreased. Grey are known Tfs and purple are ChIP validated TFs.




Figure 9: Late-L3 vs Mid-L3 G85R and WT samples. Plotting all genes that are exclusively significantly differentially expressed in G85R or WT comparisons but not those that are shared. Size of the marker is proportional to the FDR in G85R LL3 vs ML3. Color is indicative of greater difference in logFC between G85R and WT LL3 vs ML3.